Bio-DK-Mulsion™ supplies 125 mcg (5,000 IU) of vitamin D3 and 300 mcg of vitamin K (as K1 phytonadione and K2 menaquinone-7) in a micro-emulsion for enhanced absorption and utilization. Clinical data shows that the emulsified form increases bioavailability over 200% compared to the non-emulsified form. In addition, Bio-DK-Mulsion™ is absorbed first through the lymphatic system, the body's preferred route of administration, and then transported to the blood circulation. 
Clinical data shows this emulsified form increases
bioavailability over 200% compared to the
non-emulsified form. In addition, Bio-DK Caps™
and Bio-DK-Mulsion™ are absorbed first through
the lymphatic system, the body’s preferred route of
administration, and then transported to the blood
circulation.
1.  Vitamin D deficiency causes a reduction in calcium
absorption.
2.  Production of parathyroid (PTH) hormone is
increased to maintain blood calcium levels.
3.  Increase PTH results in increased urinary excretion of
phosphorous, which leads to hypophosphatemia.
4.  Insufficient calcium phosphate results in deposition
of unmineralized collagen matrix on the endosteal
(inside) and periosteal (outside) surface of bones.
5.  When the collagen matrix hydrates and swells,
it causes pressure on the sensory-innervated
periosteum resulting in pain.⁽3)
Vitamin D, a nutrient synthesized in our skin when
exposed to sunlight, can also be found in some foods
such as oily fish, beef liver, egg yolks, mushrooms and
some fortified foods such as milk and breakfast cereal.
Surprisingly, however, nearly half of the American
population is deficient in vitamin D,⁽1⁾ with serum of
25-hydroxy vitamin D concentrations less than 20 ng/
mL (50 nmol/L).
Several clinical investigations have shown vitamin
D deficiency to be particularly common among
people with musculoskeletal pain.⁽⁴,⁵⁾ In addition, a
study on patients with osteoarthritis (OA), a chronic
degenerative disease of articular cartilage, shows
vitamin D to have a positive influence on healthy
inflammatory pathways.⁽⁶⁾
While we are familiar with the importance of vitamin
D in calcium absorption and bone metabolism, many
may not be aware of burgeoning research on vitamin
D, and the widening range of applications available
for cholecalciferol, which can be classified as both a
vitamin and a pro-hormone.⁽2)
Vitamin D Deficiency and Musculoskeletal Health
Vitamin D deficiency is associated with dull, achy
musculoskeletal pain that is incompletely responsive
to both pharmacologic and manual therapies. The pain
may be widespread or confined to a particular area,
most commonly the lower back and lumbar spine. The
process by which this occurs has been clearly defined:
Clinical Applications
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Healthy Calcium Balance
Bone Health
Cardiovascular Support
Immune Function
Neurological Benefits
Healthy Weight Management
Blood Sugar Regulatio